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Loss of Macrophage LDL Receptor Related Protein 1 (LRP1) Confers Resistance to the Anti-atherogenic Effects of TNFα Inhibition

OBJECTIVE: Anti-atherosclerotic effects of TNFα blockade in patients with systemic inflammatory states are not conclusively demonstrated, which suggests that effects depend on the cause of inflammation. Macrophage LRP1 and apoE contribute to inflammation through different pathways. We studied the an...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Zhu, Lin, Giunzioni, Ilaria, Tavori, Hagai, Covarrubias, Roman, Ding, Lei, Zhang, Youmin, Ormseth, Michelle, Major, Amy S., Stafford, John M., Linton, MacRae F., Fazio, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346022/
https://ncbi.nlm.nih.gov/pubmed/27365402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307736
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