Adenosine A(2A) receptor agonist prevents cardiac remodeling and dysfunction in spontaneously hypertensive male rats after myocardial infarction

BACKGROUND: This work evaluated the hypothesis that 3,4-methylenedioxybenzoyl-2-thienylhydrazone (LASSBio-294), an agonist of adenosine A(2A) receptor, could be beneficial for preventing cardiac dysfunction due to hypertension associated with myocardial infarction (MI). METHODS: Male spontaneously h...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: da Silva, Jaqueline S, Gabriel-Costa, Daniele, Sudo, Roberto T, Wang, Hao, Groban, Leanne, Ferraz, Emanuele B, Nascimento, José Hamilton M, Fraga, Carlos Alberto M, Barreiro, Eliezer J, Zapata-Sudo, Gisele
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345997/
https://ncbi.nlm.nih.gov/pubmed/28293100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S113289
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