Cardiomyocyte-specific deletion of the G protein-coupled estrogen receptor (GPER) leads to left ventricular dysfunction and adverse remodeling: a sex-specific gene profiling analysis

Activation of G protein-coupled estrogen receptor (GPER) by its agonist, G1, protects the heart from stressors such as pressure-overload, ischemia, a high-salt diet, estrogen loss, and aging, in various male and female animal models. Due to nonspecific effects of G1, the exact functions of cardiac G...

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Gepubliceerd in:Biochim Biophys Acta
Hoofdauteurs: Wang, Hao, Sun, Xuming, Chou, Jeff, Lin, Marina, Ferrario, Carlos M., Zapata-Sudo, Gisele, Groban, Leanne
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385168/
https://ncbi.nlm.nih.gov/pubmed/27725247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.10.003
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