Phylogenetic factorization of compositional data yields lineage-level associations in microbiome datasets

Marker gene sequencing of microbial communities has generated big datasets of microbial relative abundances varying across environmental conditions, sample sites and treatments. These data often come with putative phylogenies, providing unique opportunities to investigate how shared evolutionary his...

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Veröffentlicht in:PeerJ
Hauptverfasser: Washburne, Alex D., Silverman, Justin D., Leff, Jonathan W., Bennett, Dominic J., Darcy, John L., Mukherjee, Sayan, Fierer, Noah, David, Lawrence A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: PeerJ Inc. 2017
Schlagworte:
Computational Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345826/
https://ncbi.nlm.nih.gov/pubmed/28289558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2969
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