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The Potential Role of Lysosomal Sequestration in Sunitinib Resistance of Renal Cell Cancer
Renal cell carcinoma (RCC) is a highly vascularized tumor type, which is often associated with inactivated mutations in the von Hippel-Lindau gene that drives proangiogenic signaling pathways. As such, new therapies for the treatment of RCC have largely been focused on blocking angiogenesis. Sunitin...
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| Publicado en: | J Kidney Cancer VHL |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Codon Publications
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5345522/ https://ncbi.nlm.nih.gov/pubmed/28326274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15586/jkcvhl.2015.44 |
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