Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes

BACKGROUND: Cardiotoxicity remains an important concern in drug discovery. Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have become an attractive platform to evaluate cardiotoxicity. However, the consistency between human embryonic stem cell-derived cardiomyocytes (hESC-CMs) and hum...

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Udgivet i:Stem Cell Res Ther
Main Authors: Zhao, Qi, Wang, Xijie, Wang, Shuyan, Song, Zheng, Wang, Jiaxian, Ma, Jing
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345165/
https://ncbi.nlm.nih.gov/pubmed/28279214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0473-x
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