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Nix restores mitophagy and mitochondrial function to protect against PINK1/Parkin-related Parkinson’s disease
Therapeutic targets are needed to develop neuroprotective treatments for Parkinson’s disease (PD). Mitophagy, the selective autophagic elimination of dysfunctional mitochondria, is essential for the maintenance of mitochondrial integrity and is predominantly regulated by the PINK1/Parkin-mediated pa...
Tallennettuna:
| Julkaisussa: | Sci Rep |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5345073/ https://ncbi.nlm.nih.gov/pubmed/28281653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44373 |
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