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IL-17 induces reactive astrocytes and up-regulation of vascular endothelial growth factor (VEGF) through JAK/STAT signaling

Spinal cord injury is a grave neurological disability resulting in neuron degeneration and permanent paralysis. The inflammation triggered by the injury would promote the spinal cord lesion in turn. Activated astrocytes during inflammatory response could promote glial scar formation and contribute t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: You, Tao, Bi, Yihui, li, Jun, Zhang, Mingkai, Chen, Xuezhou, Zhang, Keke, Li, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345044/
https://ncbi.nlm.nih.gov/pubmed/28281545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41779
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