Defining imaging biomarker cut-points for brain aging and Alzheimer’s disease

INTRODUCTION: Our goal was to develop cut-points for amyloid PET, tau PET, FDG PET, and MRI cortical thickness. METHODS: We examined five methods for determining cut-points. RESULTS: The reliable worsening method produced a cut-point only for amyloid PET. The specificity, sensitivity, and accuracy o...

詳細記述

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書誌詳細
出版年:Alzheimers Dement
主要な著者: Jack, Clifford R., Wiste, Heather J., Weigand, Stephen D., Therneau, Terry M., Lowe, Val J., Knopman, David S., Gunter, Jeffrey L., Senjem, Matthew L., Jones, David T., Kantarci, Kejal, Machulda, Mary M., Mielke, Michelle M., Roberts, Rosebud O., Vemuri, Prashanthi, Reyes, Denise A., Petersen, Ronald C.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344738/
https://ncbi.nlm.nih.gov/pubmed/27697430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2016.08.005
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