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Systematic and functional characterization of novel androgen receptor variants arising from alternative splicing in the ligand-binding domain
The presence of intact ligand-binding domain (LBD) ensures the strict androgen-dependent regulation of androgen receptor (AR): binding of androgen induces structural reorganization of LBD resulting in release of AR from HSP90, suppression of nuclear export which otherwise dominates over import and n...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5344735/ https://ncbi.nlm.nih.gov/pubmed/27694897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.313 |
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