Activity-Mediated AMPA Receptor Remodeling, Driven by Alternative Splicing in the Ligand-Binding Domain

The AMPA-type glutamate receptor (AMPAR) subunit composition shapes synaptic transmission and varies throughout development and in response to different input patterns. Here, we show that chronic activity deprivation gives rise to synaptic AMPAR responses with enhanced fidelity. Extrasynaptic AMPARs...

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Detalhes bibliográficos
Main Authors: Penn, Andrew C., Balik, Ales, Wozny, Christian, Cais, Ondrej, Greger, Ingo H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2012
Assuntos:
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500689/
https://ncbi.nlm.nih.gov/pubmed/23141062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.08.010
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