Activity-Mediated AMPA Receptor Remodeling, Driven by Alternative Splicing in the Ligand-Binding Domain

The AMPA-type glutamate receptor (AMPAR) subunit composition shapes synaptic transmission and varies throughout development and in response to different input patterns. Here, we show that chronic activity deprivation gives rise to synaptic AMPAR responses with enhanced fidelity. Extrasynaptic AMPARs...

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Autores principales: Penn, Andrew C., Balik, Ales, Wozny, Christian, Cais, Ondrej, Greger, Ingo H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500689/
https://ncbi.nlm.nih.gov/pubmed/23141062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.08.010
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