Frontotemporal dementia with the V337M MAPT mutation: Tau-PET and pathology correlations

OBJECTIVE: To assess the efficacy of [(18)F]AV1451 PET in visualizing tau pathology in vivo in a patient with frontotemporal dementia (FTD) associated with the V337M microtubule-associated protein tau (MAPT) mutation. METHODS: MAPT mutations are associated with the deposition of hyperphosphorylated...

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Udgivet i:Neurology
Main Authors: Spina, Salvatore, Schonhaut, Daniel R., Boeve, Bradley F., Seeley, William W., Ossenkoppele, Rik, O'Neil, James P., Lazaris, Andreas, Rosen, Howard J., Boxer, Adam L., Perry, David C., Miller, Bruce L., Dickson, Dennis W., Parisi, Joseph E., Jagust, William J., Murray, Melissa E., Rabinovici, Gil D.
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344079/
https://ncbi.nlm.nih.gov/pubmed/28130473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000003636
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