Preferential tau aggregation in von Economo neurons and fork cells in frontotemporal lobar degeneration with specific MAPT variants

Tau aggregation is a hallmark feature in a subset of patients with frontotemporal dementia (FTD). Early and selective loss of von Economo neurons (VENs) and fork cells within the frontoinsular (FI) and anterior cingulate cortices (ACC) is observed in patients with sporadic behavioral variant FTD (bv...

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Dades bibliogràfiques
Publicat a:Acta Neuropathol Commun
Autors principals: Lin, Li-Chun, Nana, Alissa L., Hepker, Mackenzie, Hwang, Ji-Hye Lee, Gaus, Stephanie E., Spina, Salvatore, Cosme, Celica G., Gan, Li, Grinberg, Lea T., Geschwind, Daniel H., Coppola, Giovanni, Rosen, Howard J., Miller, Bruce L., Seeley, William W.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805408/
https://ncbi.nlm.nih.gov/pubmed/31640778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0809-0
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