Preferential tau aggregation in von Economo neurons and fork cells in frontotemporal lobar degeneration with specific MAPT variants

Tau aggregation is a hallmark feature in a subset of patients with frontotemporal dementia (FTD). Early and selective loss of von Economo neurons (VENs) and fork cells within the frontoinsular (FI) and anterior cingulate cortices (ACC) is observed in patients with sporadic behavioral variant FTD (bv...

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Detalles Bibliográficos
Publicado en:Acta Neuropathol Commun
Main Authors: Lin, Li-Chun, Nana, Alissa L., Hepker, Mackenzie, Hwang, Ji-Hye Lee, Gaus, Stephanie E., Spina, Salvatore, Cosme, Celica G., Gan, Li, Grinberg, Lea T., Geschwind, Daniel H., Coppola, Giovanni, Rosen, Howard J., Miller, Bruce L., Seeley, William W.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805408/
https://ncbi.nlm.nih.gov/pubmed/31640778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0809-0
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