Frontotemporal dementia with the V337M MAPT mutation: Tau-PET and pathology correlations

OBJECTIVE: To assess the efficacy of [(18)F]AV1451 PET in visualizing tau pathology in vivo in a patient with frontotemporal dementia (FTD) associated with the V337M microtubule-associated protein tau (MAPT) mutation. METHODS: MAPT mutations are associated with the deposition of hyperphosphorylated...

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Publicat a:Neurology
Autors principals: Spina, Salvatore, Schonhaut, Daniel R., Boeve, Bradley F., Seeley, William W., Ossenkoppele, Rik, O'Neil, James P., Lazaris, Andreas, Rosen, Howard J., Boxer, Adam L., Perry, David C., Miller, Bruce L., Dickson, Dennis W., Parisi, Joseph E., Jagust, William J., Murray, Melissa E., Rabinovici, Gil D.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344079/
https://ncbi.nlm.nih.gov/pubmed/28130473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000003636
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