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Cytochrome P450s in human immune cells regulate IL-22 and c-Kit via an AHR feedback loop
The mechanisms how environmental compounds influence the human immune system are unknown. The environmentally sensitive transcription factor aryl hydrocarbon receptor (AHR) has immune-modulating functions and responds to small molecules. Cytochrome P4501 enzymes (CYP1) act downstream of the AHR and...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5343665/ https://ncbi.nlm.nih.gov/pubmed/28276465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44005 |
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