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The role of AHR-inducible cytochrome P450s in metabolism of polyunsaturated fatty acids

The environmental pollutant 2,3,7,8-tetrachlorodibenzo-ρ-dioxin (TCDD) is the prototype of a large number of non-genotoxic carcinogens, dietary phytochemicals and endogenous metabolites that act via binding the aryl hydrocarbon receptor (AHR). The TCDD-liganded AHR massively upregulates CYP1A1, CYP1...

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Detalles Bibliográficos
Publicado en:Drug Metab Rev
Autor Principal: Hankinson, Oliver
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026385/
https://ncbi.nlm.nih.gov/pubmed/27358009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03602532.2016.1197240
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