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The impact of the RBM4-initiated splicing cascade on modulating the carcinogenic signature of colorectal cancer cells

A growing body of studies has demonstrated that dysregulated splicing profiles constitute pivotal mechanisms for carcinogenesis. In this study, we identified discriminative splicing profiles of colorectal cancer (CRC) cells compared to adjacent normal tissues using deep RNA-sequencing (RNA-seq). The...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Lin, Jung-Chun, Lee, Yuan-Chii, Liang, Yu-Chih, Fann, Yang C., Johnson, Kory R., Lin, Ying-Ju
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343574/
https://ncbi.nlm.nih.gov/pubmed/28276498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44204
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