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The impact of the RBM4-initiated splicing cascade on modulating the carcinogenic signature of colorectal cancer cells

A growing body of studies has demonstrated that dysregulated splicing profiles constitute pivotal mechanisms for carcinogenesis. In this study, we identified discriminative splicing profiles of colorectal cancer (CRC) cells compared to adjacent normal tissues using deep RNA-sequencing (RNA-seq). The...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Lin, Jung-Chun, Lee, Yuan-Chii, Liang, Yu-Chih, Fann, Yang C., Johnson, Kory R., Lin, Ying-Ju
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343574/
https://ncbi.nlm.nih.gov/pubmed/28276498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44204
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