The impact of the RBM4-initiated splicing cascade on modulating the carcinogenic signature of colorectal cancer cells

A growing body of studies has demonstrated that dysregulated splicing profiles constitute pivotal mechanisms for carcinogenesis. In this study, we identified discriminative splicing profiles of colorectal cancer (CRC) cells compared to adjacent normal tissues using deep RNA-sequencing (RNA-seq). The...

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Published in:Sci Rep
Main Authors: Lin, Jung-Chun, Lee, Yuan-Chii, Liang, Yu-Chih, Fann, Yang C., Johnson, Kory R., Lin, Ying-Ju
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343574/
https://ncbi.nlm.nih.gov/pubmed/28276498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44204
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