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Cell stress modulates the function of splicing regulatory protein RBM4 in translation control
RNA-binding motif protein 4 (RBM4) plays a regulatory role in alternative splicing of precursor mRNA. We show here that cell stress such as arsenite exposure induces phosphorylation of RBM4 at serine 309 and also drives its cytoplasmic accumulation and targeting to stress granule via the MKK(3/6)-p3...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1893002/ https://ncbi.nlm.nih.gov/pubmed/17284590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611015104 |
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