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Are dust mite allergens more abundant and/or more stable than other Dermatophagoides pteronyssinus proteins?

RNA-seq and denaturation studies demonstrated that allergens are among the most highly expressed and stable proteins from Dermatophagoides pteronyssinus. The combination of high levels of transcription and stability for the major allergens Der p 1, Der p 2, and Der p 23 is rare.

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Bibliografiske detaljer
Udgivet i:J Allergy Clin Immunol
Main Authors: Ogburn, Ryenne N., Randall, Thomas A., Xu, Yingrong, Roberts, Julia H., Mebrahtu, Betelihem, Karnuta, Jaret M., Rider, S. Dean, Kissling, Grace E., London, Robert E., Pomés, Anna, Arlian, Larry, Fitzgerald, Michael C., Mueller, Geoffrey A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342938/
https://ncbi.nlm.nih.gov/pubmed/27771129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.08.016
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