Are dust mite allergens more abundant and/or more stable than other Dermatophagoides pteronyssinus proteins?

RNA-seq and denaturation studies demonstrated that allergens are among the most highly expressed and stable proteins from Dermatophagoides pteronyssinus. The combination of high levels of transcription and stability for the major allergens Der p 1, Der p 2, and Der p 23 is rare.

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Ogburn, Ryenne N., Randall, Thomas A., Xu, Yingrong, Roberts, Julia H., Mebrahtu, Betelihem, Karnuta, Jaret M., Rider, S. Dean, Kissling, Grace E., London, Robert E., Pomés, Anna, Arlian, Larry, Fitzgerald, Michael C., Mueller, Geoffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342938/
https://ncbi.nlm.nih.gov/pubmed/27771129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.08.016
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