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CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy

CD103+ tumor-infiltrating lymphocytes (TIL) have been linked to specific epithelial infiltration and a prolonged survival in high-grade serous epithelial ovarian cancer (HGSC). However, whether these cells are induced as part of an ongoing anti-HGSC immune response or represent non-specifically expa...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Komdeur, Fenne L., Wouters, Maartje C.A., Workel, Hagma H., Tijans, Aline M., Terwindt, Anouk L.J., Brunekreeft, Kim L., Plat, Annechien, Klip, Harry G., Eggink, Florine A., Leffers, Ninke, Helfrich, Wijnand, Samplonius, Douwe F., Bremer, Edwin, Wisman, G. Bea A., Daemen, Toos, Duiker, Evelien W., Hollema, Harry, Nijman, Hans W., de Bruyn, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342728/
https://ncbi.nlm.nih.gov/pubmed/27650547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12077
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