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Human PDE4D isoform composition is deregulated in primary prostate cancer and indicative for disease progression and development of distant metastases

Phosphodiesterase 4D7 was recently shown to be specifically over-expressed in localized prostate cancer, raising the question as to which regulatory mechanisms are involved and whether other isoforms of this gene family (PDE4D) are affected under the same conditions. We investigated PDE4D isoform co...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Böttcher, René, Dulla, Kalyan, van Strijp, Dianne, Dits, Natasja, Verhoef, Esther I., Baillie, George S., van Leenders, Geert J.L.H., Houslay, Miles D., Jenster, Guido, Hoffmann, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342582/
https://ncbi.nlm.nih.gov/pubmed/27683107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12204
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