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Targeting Notch signaling as a novel therapy for retinoblastoma

Retinoblastoma is the most common intraocular malignancy of childhood. Notch plays a key role in retinal cells from which retinoblastomas arise, and we therefore studied the role of Notch signaling in promoting retinoblastoma proliferation. Moderate or strong nuclear expression of Hes1 was found in...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Asnaghi, Laura, Tripathy, Arushi, Yang, Qian, Kaur, Harpreet, Hanaford, Allison, Yu, Wayne, Eberhart, Charles G.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342532/
https://ncbi.nlm.nih.gov/pubmed/27661116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12142
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