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Targeting Notch signaling as a novel therapy for retinoblastoma

Retinoblastoma is the most common intraocular malignancy of childhood. Notch plays a key role in retinal cells from which retinoblastomas arise, and we therefore studied the role of Notch signaling in promoting retinoblastoma proliferation. Moderate or strong nuclear expression of Hes1 was found in...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Asnaghi, Laura, Tripathy, Arushi, Yang, Qian, Kaur, Harpreet, Hanaford, Allison, Yu, Wayne, Eberhart, Charles G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342532/
https://ncbi.nlm.nih.gov/pubmed/27661116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12142
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