GBM-associated mutations and altered protein expression are more common in young patients

BACKGROUND: Geriatric glioblastoma (GBM) patients have a poorer prognosis than younger patients, but IDH1/2 mutations (more common in younger patients) confer a favorable prognosis. We compared key GBM molecular alterations between an elderly (age ≥ 70) and younger (18 < = age < = 45) cohort t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ferguson, Sherise D., Xiu, Joanne, Weathers, Shiao-Pei, Zhou, Shouhao, Kesari, Santosh, Weiss, Stephanie E., Verhaak, Roeland G., Hohl, Raymond J., Barger, Geoffrey R., Reddy, Sandeep K., Heimberger, Amy B.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342491/
https://ncbi.nlm.nih.gov/pubmed/27579614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11617
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