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MDS shows a higher expression of hTERT and alternative splice variants in unactivated T-cells

Telomere instability and telomerase reactivation are believed to play an important role in the development of myelodysplastic syndromes (MDS). Abnormal enzymatic activity of human telomerase reverse transcriptase (hTERT), and its alternative splice variants have been reported to account for deregula...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Dong, Wen, Wu, Lei, Sun, Houfang, Ren, Xiubao, Epling-Burnette, Pearlie K., Yang, Lili
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342131/
https://ncbi.nlm.nih.gov/pubmed/27655690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12115
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