Insights into Telomerase/hTERT Alternative Splicing Regulation Using Bioinformatics and Network Analysis in Cancer

The reactivation of telomerase in cancer cells remains incompletely understood. The catalytic component of telomerase, hTERT, is thought to be the limiting component in cancer cells for the formation of active enzymes. hTERT gene expression is regulated at several levels including chromatin, DNA met...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Ludlow, Andrew T., Slusher, Aaron L., Sayed, Mohammed E.
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562651/
https://ncbi.nlm.nih.gov/pubmed/31091669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050666
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