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Insights into Telomerase/hTERT Alternative Splicing Regulation Using Bioinformatics and Network Analysis in Cancer

The reactivation of telomerase in cancer cells remains incompletely understood. The catalytic component of telomerase, hTERT, is thought to be the limiting component in cancer cells for the formation of active enzymes. hTERT gene expression is regulated at several levels including chromatin, DNA met...

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Detalles Bibliográficos
Publicado en:Cancers (Basel)
Main Authors: Ludlow, Andrew T., Slusher, Aaron L., Sayed, Mohammed E.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562651/
https://ncbi.nlm.nih.gov/pubmed/31091669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050666
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