Scriptaid overcomes hypoxia-induced cisplatin resistance in both wild-type and mutant p53 lung cancer cells

Non-small cell lung cancer (NSCLC), comprising 85% of lung cancer cases, has been associated with resistance to chemo/radiotherapy. The hypoxic tumor micro-environment, where insufficient vasculature results in poor drug penetrance and sub-optimal chemotherapy in the tumor interiors contributes heav...

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Vydáno v:Oncotarget
Hlavní autoři: Pradhan, Shrikant, Mahajan, Divyank, Kaur, Prabhjot, Pandey, Namita, Sharma, Chandresh, Srivastava, Tapasya
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342127/
https://ncbi.nlm.nih.gov/pubmed/27708247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12378
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