Co-application of canavanine and irradiation uncouples anticancer potential of arginine deprivation from citrulline availability

The moderate anticancer effect of arginine deprivation in clinical trials has been linked to an induced argininosuccinate synthetase (ASS1) expression in initially ASS1-negative tumors, and ASS1-positive cancers are anticipated as non-responders. Our previous studies indicated that arginine deprivat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Kurlishchuk, Yuliya, Vynnytska-Myronovska, Bozhena, Grosse-Gehling, Philipp, Bobak, Yaroslav, Manig, Friederike, Chen, Oleg, Merker, Sebastian R., Henle, Thomas, Löck, Steffen, Stange, Daniel E., Stasyk, Oleh, Kunz, Leoni A.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341980/
https://ncbi.nlm.nih.gov/pubmed/27689335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12320
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