Dual role of ER stress in response to metabolic co-targeting and radiosensitivity in head and neck cancer cells

Arginine deprivation therapy (ADT) is a new metabolic targeting approach with high therapeutic potential for various solid cancers. Combination of ADT with low doses of the natural arginine analog canavanine effectively sensitizes malignant cells to irradiation. However, the molecular mechanisms det...

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Detalles Bibliográficos
Publicado en:Cell Mol Life Sci
Main Authors: Chen, Oleg, Manig, Friederike, Lehmann, Loreen, Sorour, Nagwa, Löck, Steffen, Yu, Zhanru, Dubrovska, Anna, Baumann, Michael, Kessler, Benedikt M., Stasyk, Oleh, Kunz-Schughart, Leoni A.
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2020
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004506/
https://ncbi.nlm.nih.gov/pubmed/33230565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03704-7
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