Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response

Adipocytes promote cancer progression and impair treatment, and have been shown to protect acute lymphoblastic leukemia (ALL) cells from chemotherapies. Here we investigate whether this protection is mediated by changes in oxidative stress. Co-culture experiments showed that adipocytes protect ALL c...

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Udgivet i:Oncotarget
Main Authors: Sheng, Xia, Tucci, Jonathan, Parmentier, Jean-Hugues, Ji, Lingyun, Behan, James W., Heisterkamp, Nora, Mittelman, Steven D.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341969/
https://ncbi.nlm.nih.gov/pubmed/27705905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12246
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