Adipocytes impair leukemia treatment in mice

Obesity is associated with increased cancer incidence and mortality. We have previously found that obesity in children is associated with a 50% increased recurrence of acute lymphoblastic leukemia (ALL) in high-risk patients. We have therefore developed novel in vivo and in vitro preclinical models...

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Autori principali: Behan, James W., Yun, Jason P., Proektor, Marina P., Ehsanipour, Ehsan A., Arutyunyan, Anna, Moses, Ara S., Avramis, Vassilios I., Louie, Stan G., Butturini, Anna, Heisterkamp, Nora, Mittelman, Steven D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756308/
https://ncbi.nlm.nih.gov/pubmed/19773440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0800
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