Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia

High hyperdiploidy (HD), the most common cytogenetic subtype of B-cell acute lymphoblastic leukemia (B-ALL), is largely curable but significant treatment-related morbidity warrants investigating the biology and identifying novel drug targets. Targeted deep-sequencing of 538 cancer-relevant genes was...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: de Smith, Adam J., Ojha, Juhi, Francis, Stephen S., Sanders, Erica, Endicott, Alyson A., Hansen, Helen M., Smirnov, Ivan, Termuhlen, Amanda M., Walsh, Kyle M., Metayer, Catherine, Wiemels, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341940/
https://ncbi.nlm.nih.gov/pubmed/27683039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12238
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