Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells

Glucorticoids (GCs) such as dexamethasone (DEX) remain important treatments for Chronic Lymphocytic Leukemia (CLL) but the mechanisms are poorly understood and resistance is inevitable. Proliferation centers (PC) in lymph nodes and bone marrow offer protection against many cytotoxic drugs and circul...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Oppermann, Sina, Lam, Avery J., Tung, Stephanie, Shi, Yonghong, McCaw, Lindsay, Wang, Guizhei, Ylanko, Jarkko, Leber, Brian, Andrews, David, Spaner, David E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2016
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341931/
https://ncbi.nlm.nih.gov/pubmed/27579615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11618
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