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Persistent janus kinase‐signaling in chronic lymphocytic leukemia patients on ibrutinib: Results of a phase I trial

Methods to deepen clinical responses to ibrutinib are needed to improve outcomes for patients with chronic lymphocytic leukemia (CLL). This study aimed to determine the safety and efficacy of combining a janus kinase (JAK)‐inhibitor with ibrutinib because JAK‐mediated cytokine‐signals support CLL ce...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Spaner, David E., McCaw, Lindsay, Wang, Guizhei, Tsui, Hubert, Shi, Yonghong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488147/
https://ncbi.nlm.nih.gov/pubmed/30843659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2042
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