Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells

Glucorticoids (GCs) such as dexamethasone (DEX) remain important treatments for Chronic Lymphocytic Leukemia (CLL) but the mechanisms are poorly understood and resistance is inevitable. Proliferation centers (PC) in lymph nodes and bone marrow offer protection against many cytotoxic drugs and circul...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Oppermann, Sina, Lam, Avery J., Tung, Stephanie, Shi, Yonghong, McCaw, Lindsay, Wang, Guizhei, Ylanko, Jarkko, Leber, Brian, Andrews, David, Spaner, David E.
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341931/
https://ncbi.nlm.nih.gov/pubmed/27579615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11618
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы