Wogonin prevents TLR4-NF-κB-medicated neuro-inflammation and improves retinal ganglion cells survival in retina after optic nerve crush

Chronic neuro-inflammation is involved in the death of retinal ganglion cells (RGCs) in glaucoma. The aim of this study is to determine whether wogonin can suppress inflammatory responses and rescue RGCs death after optic nerve crush (ONC), an ideal animal model of glaucoma. Wogonin was administered...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Xu, Yue, Yang, Boyu, Hu, Yaguang, Lu, Lin, Lu, Xi, Wang, Jiawei, Xu, Fan, Yu, Shanshan, Huang, Jingjing, Liang, Xiaoling
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341925/
https://ncbi.nlm.nih.gov/pubmed/27756890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12700
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