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Wogonin prevents TLR4-NF-κB-medicated neuro-inflammation and improves retinal ganglion cells survival in retina after optic nerve crush

Chronic neuro-inflammation is involved in the death of retinal ganglion cells (RGCs) in glaucoma. The aim of this study is to determine whether wogonin can suppress inflammatory responses and rescue RGCs death after optic nerve crush (ONC), an ideal animal model of glaucoma. Wogonin was administered...

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發表在:Oncotarget
Main Authors: Xu, Yue, Yang, Boyu, Hu, Yaguang, Lu, Lin, Lu, Xi, Wang, Jiawei, Xu, Fan, Yu, Shanshan, Huang, Jingjing, Liang, Xiaoling
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341925/
https://ncbi.nlm.nih.gov/pubmed/27756890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12700
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