Wogonin Improves Histological and Functional Outcomes, and Reduces Activation of TLR4/NF-κB Signaling after Experimental Traumatic Brain Injury

BACKGROUND: Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that contributes to neuronal damage and behavioral impairment. This study was undertaken to investigate the effects of wogonin, a flavonoid with potent anti-inflammatory properties, on functional and histological outcomes...

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Detalhes bibliográficos
Main Authors: Chen, Chien-Cheng, Hung, Tai-Ho, Wang, Yen-Ho, Lin, Chii-Wann, Wang, Pei-Yi, Lee, Chun-Yen, Chen, Szu-Fu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260265/
https://ncbi.nlm.nih.gov/pubmed/22272328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030294
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