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Activation of TrkB/Akt signaling by a TrkB receptor agonist improves long-term histological and functional outcomes in experimental intracerebral hemorrhage

Abstract Background Intracerebral hemorrhage (ICH) induces a complex sequence of apoptotic cascades that contribute to secondary neuronal damage. Tropomyosin-related kinase receptor B (TrkB) signaling plays a crucial role in promoting neuronal survival following brain damage. Methods The present stu...

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Main Authors: Chun-Hu Wu, Chien-Cheng Chen, Tai-Ho Hung, Yen-Chieh Chuang, Min Chao, Song-Kun Shyue, Szu-Fu Chen
格式: Artigo
語言:Inglês
出版: BMC 2019-07-01
叢編:Journal of Biomedical Science
主題:
Akt
在線閱讀:http://link.springer.com/article/10.1186/s12929-019-0543-8
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