Activation of TrkB/Akt signaling by a TrkB receptor agonist improves long-term histological and functional outcomes in experimental intracerebral hemorrhage

Abstract Background Intracerebral hemorrhage (ICH) induces a complex sequence of apoptotic cascades that contribute to secondary neuronal damage. Tropomyosin-related kinase receptor B (TrkB) signaling plays a crucial role in promoting neuronal survival following brain damage. Methods The present stu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chun-Hu Wu, Chien-Cheng Chen, Tai-Ho Hung, Yen-Chieh Chuang, Min Chao, Song-Kun Shyue, Szu-Fu Chen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2019-07-01
Cyfres:Journal of Biomedical Science
Pynciau:
7,8-dihydroxyflavone
Apoptosis
Akt
Intracerebral hemorrhage
TrkB
Mynediad Ar-lein:http://link.springer.com/article/10.1186/s12929-019-0543-8
Tagiau: Ychwanegu Tag
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