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PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status

PROX1 is a transcription factor with an essential role in embryonic development and determination of cell fate. In addition, PROX1 has been ascribed suppressive as well as oncogenic roles in several human cancers, including brain tumors. In this study we explored the correlation between PROX1 expres...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Roodakker, Kenney R., Elsir, Tamador, Edqvist, Per-Henrik D., Hägerstrand, Daniel, Carlson, Joseph, Lysiak, Malgorzata, Henriksson, Roger, Pontén, Fredrik, Rosell, Johan, Söderkvist, Peter, Stupp, Roger, Tchougounova, Elena, Nistér, Monica, Malmström, Annika, Smits, Anja
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341919/
https://ncbi.nlm.nih.gov/pubmed/27626492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11957
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