PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status

PROX1 is a transcription factor with an essential role in embryonic development and determination of cell fate. In addition, PROX1 has been ascribed suppressive as well as oncogenic roles in several human cancers, including brain tumors. In this study we explored the correlation between PROX1 expres...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Roodakker, Kenney R., Elsir, Tamador, Edqvist, Per-Henrik D., Hägerstrand, Daniel, Carlson, Joseph, Lysiak, Malgorzata, Henriksson, Roger, Pontén, Fredrik, Rosell, Johan, Söderkvist, Peter, Stupp, Roger, Tchougounova, Elena, Nistér, Monica, Malmström, Annika, Smits, Anja
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Gerotarget (Focus on Aging)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341919/
https://ncbi.nlm.nih.gov/pubmed/27626492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11957
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