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Sex Disparities in MGMT Promoter Methylation and Survival in Glioblastoma: Further Evidence from Clinical Cohorts

Introduction: Recent studies suggest an overrepresentation of MGMT promoter methylated tumors in females with IDHwt glioblastoma (GBM) compared to males, with a subsequent better response to alkylating treatment. Methods: To reveal sex-bound associations that may have gone unnoticed in the original...

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Publicado en:J Clin Med
Autores principales: Smits, Anja, Lysiak, Malgorzata, Magnusson, Andreas, Rosell, Johan, Söderkvist, Peter, Malmström, Annika
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913151/
https://ncbi.nlm.nih.gov/pubmed/33546098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10040556
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