The prognostic value of the myeloid-mediated immunosuppression marker Arginase-1 in classic Hodgkin lymphoma

PURPOSE: Neutrophilia is hallmark of classic Hodgkin Lymphoma (cHL), but its precise characterization remains elusive. We aimed at investigating the immunosuppressive role of high-density neutrophils in HL. EXPERIMENTAL DESIGN: First, N-HL function was evaluated in vitro, showing increased arginase...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Romano, Alessandra, Parrinello, Nunziatina Laura, Vetro, Calogero, Tibullo, Daniele, Giallongo, Cesarina, La Cava, Piera, Chiarenza, Annalisa, Motta, Giovanna, Caruso, Anastasia L., Villari, Loredana, Tripodo, Claudio, Cosentino, Sebastiano, Ippolito, Massimo, Consoli, Ugo, Gallamini, Andrea, Pileri, Stefano, Di Raimondo, Francesco
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341879/
https://ncbi.nlm.nih.gov/pubmed/27637084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12024
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