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SPARC expression in CML is associated to imatinib treatment and to inhibition of leukemia cell proliferation
BACKGROUND: SPARC is a matricellular glycoprotein with growth-inhibitory and antiangiogenic activity in some cell types. The study of this protein in hematopoietic malignancies led to conflicting reports about its role as a tumor suppressor or promoter, depending on its different functions in the tu...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3570354/ https://ncbi.nlm.nih.gov/pubmed/23383963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-60 |
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