SPARC expression in CML is associated to imatinib treatment and to inhibition of leukemia cell proliferation

BACKGROUND: SPARC is a matricellular glycoprotein with growth-inhibitory and antiangiogenic activity in some cell types. The study of this protein in hematopoietic malignancies led to conflicting reports about its role as a tumor suppressor or promoter, depending on its different functions in the tu...

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Main Authors: Giallongo, Cesarina, La Cava, Piera, Tibullo, Daniele, Barbagallo, Ignazio, Parrinello, Nunziatina, Cupri, Alessandra, Stagno, Fabio, Consoli, Carla, Chiarenza, Annalisa, Palumbo, Giuseppe A, Di Raimondo, Francesco
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570354/
https://ncbi.nlm.nih.gov/pubmed/23383963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-60
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