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Proteomic Analysis Reveals Autophagy as Pro-Survival Pathway Elicited by Long-Term Exposure with 5-Azacitidine in High-Risk Myelodysplasia

Azacytidine (5-AZA) is the standard first-choice treatment for high-risk myelodysplasia (MDS) patients. However, the clinical outcome for those patients who interrupt treatment or whose disease failed to respond is very poor. In order to identify the cellular pathways that are modified by long-term...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Romano, Alessandra, Giallongo, Cesarina, La Cava, Piera, Parrinello, Nunziatina L., Chiechi, Antonella, Vetro, Calogero, Tibullo, Daniele, Di Raimondo, Francesco, Liotta, Lance A., Espina, Virginia, Palumbo, Giuseppe A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405131/
https://ncbi.nlm.nih.gov/pubmed/28491035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00204
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